Anti-MUC2 monoclonal antibody, clone DDQ69

Antibody Isotype

IgG1

Clone

DDQ69

Species Reactivity

Human

Immunogen

The 23 amino acid VNTR region of human MUC2. This antibody is known to be specific to amino acids GTQTP.

Conjugate

Application Notes

WB (1:100-1:2000); Flow Cytometry (1:10 - 1:1000); Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200 - 1:400); Immunoprecipitation (1:10-1:500) & The optimal working dilution should be determined by the end user.

Alternative Names

MUC2; mucin 2, oligomeric mucus/gel-forming; mucin 2, intestinal/tracheal; mucin-2; intestinal mucin-2; mucin-like protein; MLP; SMUC; MUC-2;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Pathway

Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Metabolism of proteins, organism-specific biosystem; O-linked glycosylation of mucins, organism-specific biosystem; Post-translational protein modification, organism-specific biosystem; Termination of O-glycan biosynthesis, organism-specific biosystem; Vibrio cholerae infection, organism-specific biosystem;