Anti-MTHFR polyclonal antibody (DPABH-13265)

Goat Anti-Human MTHFR polyclonal antibody for IHC-P Datasheet

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Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to Human MTHFR aa 644-656 (C terminal) (Cysteine residue). (NP_005948.3).Sequence: NRPTQNARETEAP Database link: P42898
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 3.75 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
MTHFR; methylenetetrahydrofolate reductase (NAD(P)H); 5,10 methylenetetrahydrofolate reductase (NADPH); methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase (NADPH)
Entrez Gene ID
UniProt ID

Product Background


Pathway
Fluoropyrimidine Activity; Folate Metabolism; Metabolic pathways; Metabolism; Metabolism of folate and pterines; Metabolism of vitamins and cofactors; Metabolism of water-soluble vitamins and cofactors

Citations


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References


McColl, MD; Chalmers, EA; et al. Factor V Leiden, prothrombin 20210 G -> A and the MTHFR C677T mutations in childhood stroke. THROMBOSIS AND HAEMOSTASIS 81:690-694(1999).
Kovac, M; Mikovic, D; et al. FV Leiden mutation and risk of recurrent venous thromboembolism in Serbian population. JOURNAL OF THROMBOSIS AND THROMBOLYSIS 25:284-287(2008).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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