Anti-MTHFR monoclonal antibody (DCABH-12467)

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
6E4
Species Reactivity
Human, Rat
Immunogen
Recombinant protein corresponding to human MTHFR.
Conjugate
Unconjugated

Applications


Application Notes
ELISA (1:10000); WB (1:500-1:2000); Immunohistochemistry (1:200-1:1000); The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
MTHFR; methylenetetrahydrofolate reductase (NAD(P)H); 5,10 methylenetetrahydrofolate reductase (NADPH); methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase (NADPH)
Entrez Gene ID
UniProt ID

Product Background


Pathway
Fluoropyrimidine Activity, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of folate and pterines, organism-specific biosystem; Metabolism of vitamins and cofactors, organism-specific biosystem; Metabolism of water-soluble vitamins and cofactors, organism-specific biosystem;

Citations


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References


Maharshak, N; Halfon, P; et al. Increased fibrosis progression rates in hepatitis C patients carrying the prothrombin G20210A mutation. WORLD JOURNAL OF GASTROENTEROLOGY 17:5007-5013(2011).
Candito, M; Candito, E; et al. Homocysteinemia and thrombophilic factors in unexplained decompression sickness.. REVUE NEUROLOGIQUE 162:840-844(2006).

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