Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide, corresponding to residues in Human MPG (UniProt: P29372).
Applications
Application Notes
ICC/IF: 1/500; WB: 1/10000 - 1/50000; IHC-P: 1/50 - 1/100; ICC: 1/250 - 1/500; IP: 1/10 - 1/100.
Target
Alternative Names
MPG; N-methylpurine-DNA glycosylase; DNA-3-methyladenine glycosylase; alkyladenine DNA glycosylase; MDG; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; proliferation-inducing protein 11; proliferation-inducing protein 16; N-methylpurine-
Product Background
Antigen Description
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
Pathway
Base Excision Repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; Cleavage of the damaged purine, organism-specific biosystem; DNA Repair, organism-specific biosystem.
Citations
Publication ()
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COA
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