Anti-MGST3 monoclonal antibody (DCABH-287)

Mouse anti-Bovine MGST3 monoclonal antibody for ICC/IF, ELISA, IP Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
3H21DH8
Species Reactivity
Rat, Human
Immunogen
purified enzymes from bovine liver
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 2 μg/ml; In-Cell ELISA: 2 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
MGST3; microsomal glutathione S-transferase 3; microsomal GST-3; MGC127068
Entrez Gene ID
UniProt ID

Product Background


Gene summary
MGST3 (Microsomal Glutathione S-Transferase 3) is a Protein Coding gene. Among its related pathways are Metabolism and Phase II conjugation. GO annotations related to this gene include glutathione transferase activity and glutathione peroxidase activity. This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.
Antigen Description
Also functions as a glutathione peroxidase. Microsomal glutathione S-transferase 3 is an enzyme that in humans is encoded by the MGST3 gene. 0The function about MGST3 antigen include glutathione peroxidase activity; glutathione transferase activity; transferase activity.
Pathway
Biological oxidations, organism-specific biosystem; Drug metabolism - cytochrome P45, organism-specific biosystem; Drug metabolism - cytochrome P45, conserved biosystem; Glutathione conjugation, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem; Metabolism, organism-specific biosystem.

Citations


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References


RAHILLY, M; CARDER, PJ; et al. DISTRIBUTION OF GLUTATHIONE-S-TRANSFERASE ISOENZYMES IN HUMAN OVARY. JOURNAL OF REPRODUCTION AND FERTILITY 93:303-311(1991).
BANGER, KK; LOCK, EA; et al. THE CHARACTERIZATION OF GLUTATHIONE S-TRANSFERASES FROM RAT OLFACTORY EPITHELIUM. BIOCHEMICAL JOURNAL 290:199-204(1993).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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