Full length protein corresponding to Human Surb7 aa 1-144.Sequence: MADRLTQLQDAVNSLADQFCNAIGVLQQCGPPASFNNIQTAINKDQPANP TEEYAQLFAALIARTAKDIDVLIDSLPSEESTAALQAASLYKLEEENHEA ATCLEDVVYRGDMLLEKIQSALADIAQSQLKTRSGTHSQSLPDS Database link: NP_004255.2
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/1000;
Target
Alternative Names
MED21; mediator complex subunit 21; SRB7; SURB7; hSrb7; mediator of RNA polymerase II transcription subunit 21; RNAPII complex component SRB7; RNA polymerase II holoenzyme component SRB7; SRB7 suppressor of RNA polymerase B homolog;
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Pathway
Developmental Biology; Metabolism; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation
Citations
Publication ()
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