Magic™ Anti-Tau monoclonal antibody (DCABH-2626)

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS3563
Species Reactivity
Human
Immunogen
A phospho specific peptide corresponding to residues surrounding Serine 235 of Human Tau (P10636).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/10000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
MAPT; microtubule-associated protein tau; DDPAC, MAPTL; FLJ31424; FTDP 17; G protein beta1/gamma2 subunit interacting factor 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Caspase-mediated cleavage of cytoskeletal proteins, organism-specific biosystem; IL-6 Signaling Pathway, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Amadoro, G; Corsetti, V; et al. Endogenous A beta causes cell death via early tau hyperphosphorylation. NEUROBIOLOGY OF AGING 32:969-990(2011).
Davtyan, H; Ghochikyan, A; et al. Immunogenicity, Efficacy, Safety, and Mechanism of Action of Epitope Vaccine (Lu AF20513) for Alzheimer's Disease: Prelude to a Clinical Trial. JOURNAL OF NEUROSCIENCE 33:4923-4934(2013).

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