Magic™ Anti-Tau monoclonal antibody (DCABH-211)

Rabbit Anti-Human Tau (Phospho S324) monoclonal antibody for WB, IP, ICC/IF

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS3568(3)
Species Reactivity
Mouse, Rat, Human
Immunogen
Phospho specific peptide corresponding to residues surrounding Serine 324 of Human Tau.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/10000 - 1/50000; IP: 1/10 - 1/100; ICC/IF: 1/100 - 1/250
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
MAPT; microtubule-associated protein tau; DDPAC, MAPTL; FLJ31424; FTDP 17; G protein beta1/gamma2 subunit interacting factor 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Caspase-mediated cleavage of cytoskeletal proteins, organism-specific biosystem; IL-6 Signaling Pathway, organism-specific biosystem;

Citations


Have you cited DCABH-211 in a publication? Let us know and earn a reward for your research.

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

References


The association of smoking status with SARS-CoV-2 infection, hospitalization and mortality from COVID-19: a living rapid evidence review with Bayesian meta-analyses (version 7)

ADDICTION

Authors: Simons, David; Shahab, Lion; Brown, Jamie; Perski, Olga

Aims To estimate the association of smoking status with rates of (i) infection, (ii) hospitalization, (iii) disease severity and (iv) mortality from SARS-CoV-2/COVID-19 disease. Design Living rapid review of observational and experimental studies with random-effects hierarchical Bayesian meta-analyses. Published articles and pre-prints were identified via MEDLINE and medRxiv. Setting Community or hospital, no restrictions on location. Participants Adults who received a SARS-CoV-2 test or a COVID-19 diagnosis. Measurements Outcomes were SARS-CoV-2 infection, hospitalization, disease severity and mortality stratified by smoking status. Study quality was assessed (i.e. 'good', 'fair' and 'poor'). Findings Version 7 (searches up to 25 August 2020) included 233 studies with 32 'good' and 'fair' quality studies included in meta-analyses. Fifty-seven studies (24.5%) reported current, former and never smoking status. Recorded smoking prevalence among people with COVID-19 was generally lower than national prevalence. Current compared with never smokers were at reduced risk of SARS-CoV-2 infection [relative risk (RR) = 0.74, 95% credible interval (CrI) = 0.58-0.93, tau = 0.41]. Data for former smokers were inconclusive (RR = 1.05, 95% CrI = 0.95-1.17, tau = 0.17), but favoured there being no important association (21% probability of RR >= 1.1). Former compared with never smokers were at somewhat increased risk of hospitalization (RR = 1.20, CrI = 1.03-1.44, tau = 0.17), greater disease severity (RR = 1.52, CrI = 1.13-2.07, tau = 0.29) and mortality (RR = 1.39, 95% CrI = 1.09-1.87, tau = 0.27). Data for current smokers were inconclusive (RR = 1.06, CrI = 0.82-1.35, tau = 0.27; RR = 1.25, CrI = 0.85-1.93, tau = 0.34; RR = 1.22, 95% CrI = 0.78-1.94, tau = 0.49, respectively), but favoured there being no important associations with hospitalization and mortality (35% and 70% probability of RR >= 1.1, respectively) and a small but important association with disease severity (79% probability of RR >= 1.1). Conclusions Compared with never smokers, current smokers appear to be at reduced risk of SARS-CoV-2 infection, while former smokers appear to be at increased risk of hospitalization, increased disease severity and mortality from COVID-19. However, it is uncertain whether these associations are causal.

Impedance spectroscopy analysis and piezoelectric properties of (Na0.5Bi0.5)(0.94)Ba0.06TiO3+0.3wt.% Sm2O3 lead-free ceramics sintered at different conditions

FERROELECTRICS

Authors: Kennour, Sadia; Lamrani-Amaouz, Nouara; Chaouchi, Ahcene; Rguiti, Mohamed; Lorgoilloux, Yannick; Courtois, Christian

(Na0.5Bi0.5)(0.94)Ba0.06TiO3 + 0.3 wt.% Sm2O3 (named NBT-BT) lead-free piezoelectric ceramics were prepared by normal sintering. The effect of atmosphere sintering on NBT-BT ceramics was investigated through X-ray diffraction, dielectric, ferroelectric and piezoelectric characterizations. Real (Z ') and imaginary (Z '') parts of the complex impedance of the materials were also investigated. Dielectric studies exhibit a diffuse transition phase and are characterized by a temperature and frequency dispersion of permittivity, and this relaxation has been modeled using the modified Curie-Weiss law. The variation of the imaginary part (Z '') of impedance with frequency at various temperatures shows that the Z '' values reach a maxima peak (Z ''(max)). The appearance of single semicircle in the Nyquist plots (Z '' vs Z ') pattern at high temperatures suggests that the electrical process occurring in the material has a relaxation process possibly due to the contribution of bulk material only. It shows that the compound exhibit negative temperature coefficient of resistance (NTCR) type behavior usually found in semiconductors. The bulk resistance of the material decreases with rising temperatures similar to a semiconductor, and the Nyquist plot showed the negative temperature coefficient of resistance (NTCR) character of materials. Also, the frequency-dependent AC conductivity at different temperatures indicated that the conduction process is thermally activated process. The plots of the relaxation times tau(Z)'' and tau(M)'' as a function of temperature follow the Arrhenius law, where a single slope is observed with activation energy values come to near 1.70.

Online Inquiry

Name:
Phone: *
E-mail Address: *
Technology Interest:
Type of Organization:
Service & Products Interested: *
Project Description:
Verification code
Click image to refresh the verification code.

Related Products

Related Resources

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

Inquiry Basket