Anti-MAPK9 (aa 1-16) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide corresponding to amino acids 1-16 of rat Mapk9. The sequence is MSDSKSDGQFYSVQVA

Conjugate

Application Notes

WB: 1:500. & The optimal working dilution should be determined by the end user.

Alternative Names

MAPK9; mitogen-activated protein kinase 9; SAPK; MAPK 9; p54-alpha; SAPK-alpha; MAP kinase 9; c-Jun N-terminal kinase 2; stress-activated protein kinase JNK2; stress activated protein kinase alpha II;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases are multifunctional proteins. They are involved in a wide variety of cellular processes such as growth, proliferation, differentiation, transcription regulation, and development. They function in stress responses, apoptosis, inflammation and transformation. For example, this kinase plays a dominant role in mediating proliferation of lung cancer and prostate cancer cells, and in regulation of osmotic stress-induced tight junction disruption. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

Pathway

Activated TLR4 signalling; Adipocytokine signaling pathway; Cellular Senescence; Chagas disease (American trypanosomiasis)