Specifications
Immunogen
This antibody is an auto-antibody derived from a DZB rat that had developed membranous glomerulopathy upon exposure to mercuric chloride (Aten et al. 1995).
Target
Alternative Names
LAMA1; laminin, alpha 1; laminin subunit alpha-1; laminin-1;
Product Background
Antigen Description
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Pathway
Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem.
Citations
Publication ()
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