Anti-LRRC7 polyclonal antibody (DPABH-20813)

Rabbit anti-Human LAP1 (N-terminal) polyclonal antibody for WB, IHC-P, IHC-Fr, ICC/IF Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Human
Immunogen
Synthetic peptide to N terminal region of LAP1 conjugated to an immunogenic carrier protein.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/300 - 1/2000; IHC-P: 1/300 - 1/2000; IHC-Fr: 1/300 - 1/2000; ICC/IF: 1/200.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
LRRC7; leucine rich repeat containing 7; DENSIN; leucine-rich repeat-containing protein 7; densin-180
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression. Leucine rich repeat containing 7 also known as LRRC7, Densin-180, or LAP1 is a protein which in humans is encoded by the LRRC7 gene. 0The function about LRRC7 antigen include protein binding.

Citations


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References


MATSUOKA, K; TAOKA, M; et al. A NUCLEAR FACTOR-CONTAINING THE LEUCINE-RICH REPEATS EXPRESSED IN MURINE CEREBELLAR NEURONS. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91:9670-9674(1994).
Fournier, AE; Gould, GC; et al. Truncated soluble Nogo receptor binds Nogo-66 and blocks inhibition of axon growth by myelin. JOURNAL OF NEUROSCIENCE 22:8876-8883(2002).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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