Rabbit Anti-Human LOX (internal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human Lysyl oxidase

Conjugate

Application Notes

WB: 1:500-1:2000

General Notes

This product (Catalog No. DPABH-15528) is a rabbit-derived IgG polyclonal antibody raised against human LOX. This antibody exhibits cross-reactivity with LOX from mouse. It has been affinity purified by protein A. This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections.
DPABH-15528 is suitable for use in Western blot (WB) (1:500–1:2,000) application.
DPABH-15528 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

LYOX; Lysyl oxidase; Protein-lysine 6-oxidase

Entrez Gene ID

UniProt ID