LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms
Pathway
Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DCABH-12204 in a publication? Let us know and earn a reward for your research.
Tanaka, T; Rabbitts, TH; et al. Selection of complementary single-variable domains for building monoclonal antibodies to native proteins. NUCLEIC ACIDS RESEARCH 37:-(2009).
Jaffredo, T; Bollerot, K; et al. Tracing the hemangioblast during embryogenesis: developmental relationships between endothelial and hematopoietic cells. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY 49:269-277(2005).
Payment methods we support:
Invoice / Purchase Order
Credit card
My Review for Anti-LMO2 monoclonal antibody
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.