LIG3 (NP_039269, 823 a.a. ~ 922 a.a) partial recombinant protein with GST tag. The sequence is TKSSPVKVGEKRKAADETLCQTKVLLDIFTGVRLYLPPSTPDFSRLRRYFVAFDGDLVQE FDMTSATHVLGSRDKNPAAQQVSPEWIWACIRKRRLVAPC
Conjugate
Unconjugated
Target
Alternative Names
LIG3; ligase III, DNA, ATP-dependent; LIG2; DNA ligase 3; ligase II, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 3;
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Pathway
BER complex; Base excision repair; Resolution of AP sites via the single-nucleotide replacement pathway.
Citations
Publication ()
Have you cited DPAB-DC1852 in a publication? Let us know and earn a reward for your research.
My Review for Anti-LIG3 (aa 823-922) polyclonal antibody
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Publication 
Loading ......
