General Notes
This product (Catalog No. DPABH-19540) is a rabbit-derived polyclonal antibody raised against human LIAS, targeting the amino acid region 86–309 of the protein. It has been affinity purified by Protein A. Lipoic acid synthase (LIAS or LASY) is a mitochondrial enzyme that catalyzes the final step in the de novo biosynthesis of lipoic acid, an essential antioxidant cofactor. It inserts two sulfur atoms into an octanoyl-ACP substrate, converting it into lipoyl-ACP, which is required for critical metabolic enzyme complexes. Deficiency is associated with severe neurological, metabolic diseases, and mitochondrial dysfunction.
DPABH-19540 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-19540 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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