LGR6 (NP_067649, 403 a.a. ~ 496 a.a) partial recombinant protein with GST tag. The sequence is ALSQAFSKDSFPKLRILEVPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEESSKRPLGL LARQAENHYDQDLDELQLEMEDSKPHPSVQCSPT
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants.
Pathway
GPCRs, Other; Signaling by Wnt; regulation of FZD by ubiquitination;
Citations
Publication ()
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