Anti-LFNG monoclonal antibody, clone FQS21402(C)

Name: Anti-LFNG monoclonal antibody, clone FQS21402(C)
SKU: DCABH-4222

Rabbit anti-Human LFNG monoclonal antibody for WB, FC

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG

Clone

FQS21402(C)

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide, corresponding to residues in Human Lunatic Fringe (UniProt: Q8NES3).

Conjugate

Unconjugated

Applications

Application Notes

WB: 1/1000 - 1/10000; Flow Cyt: 1/10 - 1/100.

Target

Alternative Names

LFNG; LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; lunatic fringe (Drosophila) homolog , lunatic fringe homolog (Drosophila); beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; SCDO3;

Entrez Gene ID

3955

UniProt ID

Q8NES3

Product Background

Antigen Description

Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning.

Pathway

Delta-Notch Signaling Pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, conserved biosystem; Other types of O-glycan biosynthesis, organism-specific biosystem; Other types of O-glycan biosynthesis, conserved biosystem; Pre-NOTCH Expression and Processing, organism-specific biosystem; Pre-NOTCH Processing in Golgi, organism-specific biosystem;

Citations