Specifications
Immunogen
Full length human recombinant protein of human LDLRAP1 produced in HEK293T cell.
Target
Alternative Names
ARH; ARH1; ARH2; FHCB1; FHCB2
Product Background
Antigen Description
The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Bock, HH; Jossin, Y; et al. Apolipoprotein E receptors are required for Reelin-induced proteasomal degradation of the neuronal adaptor protein Disabled-1. JOURNAL OF BIOLOGICAL CHEMISTRY 279:33471-33479(2004).
D'Arcangelo, G; Homayouni, R; et al. Reelin is a ligand for lipoprotein receptors. NEURON 24:471-479(1999).