Anti-LDB1 (aa 50-345) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse; Human

Immunogen

Recombinant fragment corresponding to a region within amino acids 50 and 345 of Human LDB1 (NP_003884)

Conjugate

Application Notes

WB: 1/500 - 1/3000; IHC-P: 1/100 - 1/250; ICC/IF: 1/100 - 1/200.

Alternative Names

LDB1; LIM domain binding 1; LIM domain-binding protein 1; carboxy terminal LIM domain protein 2; CLIM2; NLI; LDB-1; hLdb1; CLIM-2; nuclear LIM interactor; LIM domain-binding factor-1; LIM domain-binding factor CLIM2; carboxyl-terminal LIM domain-binding p

Entrez Gene ID

UniProt ID

Antigen Description

Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a role in the development of motor neurons. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.

Pathway

Transcriptional misregulation in cancer;