Anti-L1CAM monoclonal antibody (DCABH-418)

Mouse anti-Human L1CAM monoclonal antibody for WB, IHC-P, FC, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4H2
Species Reactivity
Human
Immunogen
Recombinant full length Human L1CAM protein (NP_000416) produced in HEK293T cells
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000; IHC-P: 1/50; Flow Cyt: 1/100; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
L1CAM; L1 cell adhesion molecule; antigen identified by monoclonal R1 , HSAS, HSAS1, MASA, MIC5, S10, SPG1; neural cell adhesion molecule L1; CD171; antigen identified by monoclonal R1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Basigin interactions, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem;

Citations


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References


Fogel, M; Harari, A; et al. A standardized staining protocol for L1CAM on formalin-fixed, paraffin-embedded tissues using automated platforms. INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS 29:E180-E183(2014).
Lee, ES; Jeong, MS; et al. A chimeric antibody to L1 cell adhesion molecule shows therapeutic effect in an intrahepatic cholangiocarcinoma model. EXPERIMENTAL AND MOLECULAR MEDICINE 44:293-302(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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