Anti-KLK2 monoclonal antibody, clone 6E7

Antibody Isotype

IgG2b

Clone

6E7

Species Reactivity

Human

Immunogen

Recombinant full length protein corresponding to Human Kallikrein 2 aa 25-261. Produced in SF9 cells.Sequence: IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVW LGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFL

Conjugate

Application Notes

WB: 1/2000; IHC-P: 1/150;

Alternative Names

KLK2; kallikrein-related peptidase 2; kallikrein 2, prostatic; kallikrein-2; tissue kallikrein-2; glandular kallikrein 2; glandular kallikrein-1; hK2; hGK-1; KLK2A2; FLJ17010; FLJ17011; MGC12201;

Entrez Gene ID

UniProt ID

Antigen Description

Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.

Pathway

Activation of Matrix Metalloproteinases, organism-specific biosystem; Coregulation of Androgen receptor activity, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; Extracellular matrix organization, organism-specific biosystem; Regulation of Androgen receptor activity, organism-specific biosystem;