Anti-KIR2DS4; KIR2DL4; KIR2DL3; KIR2DL1 monoclonal antibody (DCABH-8338)

Mouse anti-Human KIR2DS4; KIR2DL4; KIR2DL3; KIR2DL1 monoclonal antibody for ELISA, WB

Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
3I7
Species Reactivity
Human
Immunogen
Recombinant human KIR2D purified from E. coli.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/2000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
KIR2DL1; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1; killer cell immunoglobulin-like receptor 2DL1; 47.11; CD158A; cl 42
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
KIRs are human natural killer (NK) cell receptors for MHC class I molecules. Most inhibit the activity of NK cells thus preventing cell lysis. Two main families of receptors for HLA class I have been discovered on human NK cells: Killer cell Immunoglobulin-like receptors (KIR) and CD94/NKG2 heterodimers. The KIR receptors are an extremely diverse family of receptors. In addition to receptors for HLA, NK cells also express pattern recognition receptors e. g. TLRs and Nod proteins. The function about KIR2DS4; KIR2DL4; KIR2DL3; KIR2DL1 antigen include protein binding; receptor activity.
Pathway
Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Graft-versus-host disease, organism-specific biosystem; Graft-versus-host disease, conserved biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem.

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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