AOF2 (NP_055828, 753 a.a. ~ 851 a.a) partial recombinant protein with GST tag. The sequence is ADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVH GALLSGLREAGRIADQFLGAMYTLPRQATPGVPAQQSPS
This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants.
Pathway
Androgen receptor signaling pathway; Factors involved in megakaryocyte development and platelet production; Notch signaling pathway;
Citations
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