Specifications
Immunogen
Mouse spontaneous T lymphoma line TK1
Conjugate
Functional Grade
Target
Alternative Names
ITGA4; integrin alpha 4; integrin alpha-4; integrin alpha-IV; LPAM subunit alpha; VLA-4 subunit alpha; VLA-4 receptor, alpha 4 subunit; CD49 antigen-like family member D; lymphocyte Peyer patch adhesion molecules subunit alpha; CD49D;
Product Background
Antigen Description
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumor cells.
Pathway
Adaptive Immune System, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem.
Citations
Publication ()
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