Anti-Infectious Salmon Anemia Virus Nucleoprotein Antibody (DMAB6808)

Mouse anti-Infectious Salmon Anemia Virus Nucleoprotein Monoclonal antibody [clone 3D8/F13] for ELISA, WB, IP, IF Datasheet

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Alternative Names
Infectious salmon anaemia virus nucleoprotein; ISAV; ISAV Nucleoprotein; Orthomyxoviridae; Isavirus; Infectious salmon anemia virus

Product Background

Antigen Description
It recognizes a 68 kDa protein corresponding to ISAV nucleoprotein. ISAV is an enveloped virus that belongs to the family Orthomyxoviridae and genus Isavirus. Its genoma comprises eight negative-sense, single-stranded RNA segments and encodes four major structural proteins including the matrix, the nucleoprotein, and two membrane glycoproteins (hemagglutinin-esterase and gp50). ISAV infects mainly endothelial cells and leukocytes and causes a multisystemic disease characterized by high mortality with exophthalmia, pale gills, ascites, hemorrhagic liver necrosis, and renal interstitial hemorrhage. Infectious salmon anemia or anaemia (ISA) is a viral disease of Atlantic Salmon (Salmo salar) that affects fish farms in Canada, Norway, Scotland and Chile, causing severe losses to infected farms. The disease is listed as a non-exotic disease of the EU and is therefore watched closely by the European Community Reference Laboratory for Fish Diseases. The aetiological agent of ISA is the infectious salmon anemia virus (ISAV). ISAV, a RNA virus, is the only species in the genus "Isavirus" which is in the family Orthomyxoviridae.


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Krossoy, B; Devold, M; et al. Cloning and identification of the infectious salmon anaemia virus haemagglutinin. JOURNAL OF GENERAL VIROLOGY 82:1757-1765(2001).
Hetland, DL; Jorgensen, SM; et al. In situ localisation of major histocompatibility complex class I and class II and CD8 positive cells in infectious salmon anaemia virus (ISAV)-infected Atlantic salmon. FISH & SHELLFISH IMMUNOLOGY 28:30-39(2010).

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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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