Anti-Infectious Salmon Anemia Virus Nucleoprotein Antibody (DMAB6808)

Mouse anti-Infectious Salmon Anemia Virus Nucleoprotein Monoclonal antibody [clone 3D8/F13] for ELISA, WB, IP, IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
3D8/F13
Conjugate
Unconjugated

Target


Alternative Names
Infectious salmon anaemia virus nucleoprotein; ISAV; ISAV Nucleoprotein; Orthomyxoviridae; Isavirus; Infectious salmon anemia virus

Product Background


Antigen Description
It recognizes a 68 kDa protein corresponding to ISAV nucleoprotein. ISAV is an enveloped virus that belongs to the family Orthomyxoviridae and genus Isavirus. Its genoma comprises eight negative-sense, single-stranded RNA segments and encodes four major structural proteins including the matrix, the nucleoprotein, and two membrane glycoproteins (hemagglutinin-esterase and gp50). ISAV infects mainly endothelial cells and leukocytes and causes a multisystemic disease characterized by high mortality with exophthalmia, pale gills, ascites, hemorrhagic liver necrosis, and renal interstitial hemorrhage. Infectious salmon anemia or anaemia (ISA) is a viral disease of Atlantic Salmon (Salmo salar) that affects fish farms in Canada, Norway, Scotland and Chile, causing severe losses to infected farms. The disease is listed as a non-exotic disease of the EU and is therefore watched closely by the European Community Reference Laboratory for Fish Diseases. The aetiological agent of ISA is the infectious salmon anemia virus (ISAV). ISAV, a RNA virus, is the only species in the genus "Isavirus" which is in the family Orthomyxoviridae.

Citations


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References


Kibenge, FSB; Garate, ON; et al. Isolation and identification of infectious salmon anaemia virus (ISAV) from Coho salmon in Chile. DISEASES OF AQUATIC ORGANISMS 45:9-18(2001).
Aspehaug, V; Falk, K; et al. Infectious salmon anemia virus (ISAV) genomic segment 3 encodes the viral nucleoprotein (NP), an RNA-binding protein with two monopartite nuclear localization signals (NLS). VIRUS RESEARCH 106:51-60(2004).

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