Anti-Infectious Salmon Anemia Virus Nucleoprotein Antibody (DMAB6808)

Mouse anti-Infectious Salmon Anemia Virus Nucleoprotein Monoclonal antibody [clone 3D8/F13] for ELISA, WB, IP, IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
3D8/F13
Conjugate
Unconjugated

Target


Alternative Names
Infectious salmon anaemia virus nucleoprotein; ISAV; ISAV Nucleoprotein; Orthomyxoviridae; Isavirus; Infectious salmon anemia virus

Product Background


Antigen Description
It recognizes a 68 kDa protein corresponding to ISAV nucleoprotein. ISAV is an enveloped virus that belongs to the family Orthomyxoviridae and genus Isavirus. Its genoma comprises eight negative-sense, single-stranded RNA segments and encodes four major structural proteins including the matrix, the nucleoprotein, and two membrane glycoproteins (hemagglutinin-esterase and gp50). ISAV infects mainly endothelial cells and leukocytes and causes a multisystemic disease characterized by high mortality with exophthalmia, pale gills, ascites, hemorrhagic liver necrosis, and renal interstitial hemorrhage. Infectious salmon anemia or anaemia (ISA) is a viral disease of Atlantic Salmon (Salmo salar) that affects fish farms in Canada, Norway, Scotland and Chile, causing severe losses to infected farms. The disease is listed as a non-exotic disease of the EU and is therefore watched closely by the European Community Reference Laboratory for Fish Diseases. The aetiological agent of ISA is the infectious salmon anemia virus (ISAV). ISAV, a RNA virus, is the only species in the genus "Isavirus" which is in the family Orthomyxoviridae.

Citations


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References


McBeath, SJ; Ellis, LM; et al. Rapid development of polyclonal antisera against infectious salmon anaemia virus and its optimization and application as a diagnostic tool. JOURNAL OF FISH DISEASES 29:293-300(2006).
Aamelfot, M; Dale, OB; et al. Expression of the Infectious Salmon Anemia Virus Receptor on Atlantic Salmon Endothelial Cells Correlates with the Cell Tropism of the Virus. JOURNAL OF VIROLOGY 86:10571-10578(2012).

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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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