Anti-Infectious Pancreatic Necrosis Virus Antibody (DMAB6813)

Mouse anti-Infectious Pancreatic Necrosis Virus Monoclonal antibody [clone 3G10/G2] for ELISA, WB, IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
3G10/G2
Conjugate
Unconjugated

Target


Alternative Names
Infectious Pancreatic Necrosis Virus; IPNV; NNV

Product Background


Antigen Description
IPNV is a single-shelled, non-enveloped virus that belongs to the family Birnaviridae. Its genoma comprises a bisegmented double-stranded RNA, the segment B encodes VP1 and the segment A yields a polyprotein, pVP2-VP4-VP3 and a small protein (VP5) dispensable for viral replication. The polyprotein is autocatalytically cleaved by the endoprotease VP4 to release the structural proteins pVP2 (62 kDa) and VP3. pVP2 is processed during virus maturation into VP2 (54 kDa) constituting the outer capsid component. IPNV is responsible for infectious pancreatic necrosis, a contagious fish disease characterized by severe damage to the internal organs and tissues with a high mortality among salmonids. Infectious pancreatic necrosis (IPN) is a severe viral disease of salmonid fish. It is caused by Infectious Pancreatic Necrosis Virus, which is a member of the birnaviridae family. This disease mainly affects young salmonids, such as trout or salmon, of less than 6 months, although adult fish may carry the virus without showing symptoms. Resistance to infection develops more rapidly in warmer water. It is highly contagious and found worldwide, however some regions have managed to eradicate or greatly reduced the incidence of disease. The disease is normally spread horizontally via infected water but spread also occurs vertically. It is not a zoonosis.

Citations


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References


Savas, H; Altinok, I; et al. Isolation of Renibacterium salmoninarum from cultured Black Sea salmon (Salmo trutta labrax): first report in Turkey. BULLETIN OF THE EUROPEAN ASSOCIATION OF FISH PATHOLOGISTS 26:238-246(2006).
Estepa, A; Coll, JM; et al. Temperature and pH requirements for viral haemorrhagic septicemia virus induced cell fusion. DISEASES OF AQUATIC ORGANISMS 28:185-189(1997).

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