Anti-ITK monoclonal antibody (CAB-6638RH)

Rabbit anti-ITK monoclonal antibody for WB, FC, IP Datasheet

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Specifications


Host Species
Rabbit
Clone
MAAG4445
Species Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues near the C-term of human Emtk/Itk/Tsk was used as immunogen.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1:1000
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ITK; IL2-inducible T-cell kinase; tyrosine-protein kinase ITK/TSK; EMT; LYK; PSCTK2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class I PI3K signaling events, organism-specific biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem; Generation of second messenger molecules, organism-specific biosystem;

Citations


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References


Fernandez-Vega, I; Quiros, LM; et al. Bruton's tyrosine kinase (Btk) is a useful marker for Hodgkin and B cell non-Hodgkin lymphoma. VIRCHOWS ARCHIV 466:229-235(2015).
Tanaka, N; Abe, H; et al. Itk, a T cell-specific tyrosine kinase, is required for CD2-mediated interleukin-2 promoter activation in the human T cell line jurkat. EUROPEAN JOURNAL OF IMMUNOLOGY 27:834-841(1997).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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