Anti-ITK monoclonal antibody (CAB-6638RH)
Rabbit anti-ITK monoclonal antibody for WB, FC, IP
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A synthetic peptide corresponding to residues near the C-term of human Emtk/Itk/Tsk was used as immunogen.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
ITK; IL2-inducible T-cell kinase; tyrosine-protein kinase ITK/TSK; EMT; LYK; PSCTK2
Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class I PI3K signaling events, organism-specific biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem; Generation of second messenger molecules, organism-specific biosystem;
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Tanaka, N; Abe, H; et al. Itk, a T cell-specific tyrosine kinase, is required for CD2-mediated interleukin-2 promoter activation in the human T cell line jurkat. EUROPEAN JOURNAL OF IMMUNOLOGY 27:834-841(1997).
Agostinelli, C; Rizvi, H; et al. Intracellular TCR-signaling Pathway Novel Markers for Lymphoma Diagnosis and Potential Therapeutic Targets. AMERICAN JOURNAL OF SURGICAL PATHOLOGY 38:1349-1359(2014).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.