Anti-ITGAV monoclonal antibody, clone 34D7 Functional Grade

Name: Anti-ITGAV monoclonal antibody, clone 34D7
SKU: DCABH-7970
Rating: 5 (1 reviews)

Mouse anti-Human ITGAV monoclonal antibody for FC, IHC-Fr, FuncS

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COA

SDS

Datasheet

Additional Formats Available

Summary

Specifications

Antibody Isotype

IgG1

Clone

34D7

Species Reactivity

Human

Immunogen

The details of the immunogen for this antibody are not available. corresponding to CD51.

Conjugate

Functional Grade

Applications

Application Notes

Flow Cyt: 1μg/10⁶ cells.

Target

Alternative Names

ITGAV; integrin, alpha V; antigen identified by monoclonal L230 , integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , MSK8, vitronectin receptor , VNRA, VTNR; integrin alpha-V; CD51; integrin alphaVbeta3; vitronectin receptor s

Entrez Gene ID

3685

UniProt ID

P06756

Product Background

Antigen Description

The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions.

Pathway

Adaptive Immune System, organism-specific biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Axon guidance, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem;

Citations