Anti-IRS2 monoclonal antibody (CAB-7730RH)

Rabbit anti-IRS2 monoclonal antibody for WB, IP, IHC Datasheet

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Specifications


Host Species
Rabbit
Clone
MAAG566
Species Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues surrounding Ser1203 of human IRS-2 was used as an immunogen.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1:5000-20000; IHC: 1:100-250
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
IRS2; insulin receptor substrate 2; IRS-2
Entrez Gene ID
UniProt ID
Q9Y4H2

Product Background


Pathway
Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem;

Citations


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References


Cintra, DE; Pauli, JR; et al. Interleukin-10 is a protective factor against diet-induced insulin resistance in liver. JOURNAL OF HEPATOLOGY 48:628-637(2008).
Norquay, LD; D'Aquino, KE; et al. Insulin Receptor Substrate-2 in beta-Cells Decreases Diabetes in Nonobese Diabetic Mice. ENDOCRINOLOGY 150:4531-4540(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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