Anti-IRF3 monoclonal antibody (DCABH-9476) Knockout Validated

Rabbit anti-Human IRF3 monoclonal antibody for WB, IHC-P, FC

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS3529Z
Species Reactivity
Mouse, Human
Immunogen
A synthetic peptide corresponding to residues surrounding the N terminus of human IRF3.
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 1/100; WB: 1/1000; IHC-P: 1/500; Flow Cyt: 1/160.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
IRF3; interferon regulatory factor 3
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Apoptosis, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Rabbit IgG Isotype Control CABT-B8382 IA Rabbit PDF Inquiry

References


Manocha, GD; Mishra, R; et al. Regulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells. JOURNAL OF NEUROINFLAMMATION 11:-(2014).
Bourteele, S; Oesterle, K; et al. Constitutive activation of the transcription factor NF-kappa B results in impaired Borna disease virus replication. JOURNAL OF VIROLOGY 79:6043-6051(2005).

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