Anti-IPO-38 monoclonal antibody (DMAB14054)

Mouse anti-Human IPO-38 monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG
Clone
TQN626
Species Reactivity
Human
Immunogen
Native purified IPO-38 from spleen cells of a patient with hairy cell leukemia.
Conjugate
Unconjugated

Applications


Application Notes
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
IPO-38 antibody; Mouse Anti-IPO-38 Monoclonal Antibody; Anti-IPO-38 Monoclonal Antibody; IPO-38 Monoclonal Antibody Mouse Anti-IPO-38 MAb; Anti-IPO-38 MAb; IPO-38 MAb

Product Background


Antigen Description
IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin"s disease and non-Hodgkin"s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 can be a useful marker of cell proliferation during monitoring of tumor progression.

Citations


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References


Mikhalap, SV; Shlapatskaya, LN; et al. Monoclonal antibody IPO-38 recognizes a novel nuclear antigen of proliferating cells.. TISSUE ANTIGENS 48:NL605-NL605(1996).
Hao, Y; Yu, YY; et al. IPO-38 is identified as a novel serum biomarker of gastric cancer based on clinical proteomics technology. JOURNAL OF PROTEOME RESEARCH 7:3668-3677(2008).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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