Anti-IPO-38 monoclonal antibody (DMAB14054)
Mouse anti-Human IPO-38 monoclonal antibody for IHC
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Native purified IPO-38 from spleen cells of a patient with hairy cell leukemia.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
IPO-38 antibody; Mouse Anti-IPO-38 Monoclonal Antibody; Anti-IPO-38 Monoclonal Antibody; IPO-38 Monoclonal Antibody Mouse Anti-IPO-38 MAb; Anti-IPO-38 MAb; IPO-38 MAb
IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin"s disease and non-Hodgkin"s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 can be a useful marker of cell proliferation during monitoring of tumor progression.
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Berezhnaya, NM; Denisevich, TV; et al. Expression of activation and proliferation markers in Mh-rhabdomyosarcoma and melanoma B-16 cells induced by some immunomodulators. EXPERIMENTAL ONCOLOGY 20:39-44(1998).
SIDORENKO, SP; SHLAPATSKAYA, LN; et al. MONOCLONAL-ANTIBODIES IPO-38 RECOGNIZING THE NUCLEAR ANTIGEN OF PROLIFERATING CELLS. EKSPERIMENTALNAYA ONKOLOGIYA 16:145-149(1994).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.