Anti-IL-2R monoclonal antibody (DMAB3843MH)

Mouse anti-Human IL-2R monoclonal antibody for FC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
OR-73
Species Reactivity
Human
Immunogen
Con-A activated human PBL T cells.
Conjugate
Unconjugated

Target


Alternative Names
CD25; CD25 antigen; IDDM10; IL 2 RA; IL 2 receptor alpha subunit; IL 2R
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
The function about IL-2R antigen include drug binding; interleukin-2 receptor activity; receptor activity.
Pathway
Arf6 trafficking events; Cytokine Signaling in Immune system; Downstream signaling in naive CD8+ T cells; IL12 signaling mediated by STAT4; Interleukin-3, 5 and GM-CSF signaling; Signaling by Interleukins.

Citations


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References


Oliveira, PRS; Dessein, H; et al. IL2RA Genetic Variants Reduce IL-2-Dependent Responses and Aggravate Human Cutaneous Leishmaniasis. JOURNAL OF IMMUNOLOGY 194:2664-2672(2015).
Barclay, SL; Yang, YM; et al. Safety and Efficacy of a tCD25 Preselective Combination Anti-HIV Lentiviral Vector in Human Hematopoietic Stem and Progenitor Cells. STEM CELLS 33:870-879(2015).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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