Anti-IgG2c monoclonal antibody [FITC] (CABT-49934MR)

Mouse anti-Rat IgG2c monoclonal antibody for FC. Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
MARG2c-5
Species Reactivity
Rat
Immunogen
IgG2c (Rat strain LOU/c)
Conjugate
FITC

Target


Alternative Names
IgG-2c; Immunoglobulin G2c; IgG2c; G2m marker; Ig gamma 2 chain C region; IGHG 2
Entrez Gene ID
UniProt ID
P20762

Product Background


Pathway
Classical antibody-mediated complement activation; Complement cascade; Creation of C4 and C2 activators; FCGR activation; Fcgamma receptor (FCGR) dependent phagocytosis;

Citations


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References


Kelly, JA; Griffin, ME; et al. Inhibition of arterial lesion progression in CD16-deficient mice: evidence for altered immunity and the role of IL-10. CARDIOVASCULAR RESEARCH 85:224-231(2010).
IKEDA, Y; SUGIYAMA, T; et al. SELECTIVE SUPPRESSION OF IGG2A SUBCLASS IN LEC RATS DURING DEVELOPMENT. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1200:277-280(1994).

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