This product (Catalog No. DPABH-22484) is a rabbit-derived polyclonal antibody raised against human IGF2BP3. It has been affinity purified by Protein A. The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. DPABH-22484 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:25–1:100) applications. DPABH-22484 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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