Anti-ID3 monoclonal antibody (DCABH-647)

Mouse anti-Human ID3 monoclonal antibody for IHC-Fr, WB, IHC-P, FC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
21E4
Species Reactivity
Human, Zebrafish
Immunogen
Recombinant full length Human ID3 produced in HEK293T cells (NP_002158).
Conjugate
Unconjugated

Applications


Application Notes
IHC-Fr: 1/100; WB: 1/500; IHC-P: 1/50; Flow Cyt: 1/100.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ID3; inhibitor of DNA binding 3, dominant negative helix-loop-helix protein; DNA-binding protein inhibitor ID-3; bHLHb25; HEIR 1; helix-loop-helix protein HEIR-1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adipogenesis, organism-specific biosystem; Id Signaling Pathway, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem;

Citations


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References


Makita, N; Bennett, PB; et al. Multiple domains contribute to the distinct inactivation properties of human heart and skeletal muscle Na+ channels. CIRCULATION RESEARCH 78:244-252(1996).
Simbulan-Rosenthal, CM; Daher, A; et al. Id3 induces a caspase-3- and -9-dependent apoptosis and mediates UVB sensitization of HPV16 E6/7 immortalized human keratinocytes. ONCOGENE 25:3649-3660(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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