Specifications
Immunogen
A synthetic peptide corresponding to residues near the hemopexin-like 1 domain of human Vitronectin.
Applications
Application Notes
WB: 1/1000 - 1/10000; IP: 1/50; IHC-P: 1/100 - 1/250.
Target
Alternative Names
VTN; vitronectin; vitronectin (serum spreading factor, somatomedin B, complement S protein); complement S protein; serum spreading factor; somatomedin B; VN; Complement S Protein; Epibolin; S Protein; S-protein; Serum Spreading Factor; Serum-spreading fac
Product Background
Antigen Description
The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Pathway
ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; FOXA1 transcription factor network, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Inflammatory Response Pathway, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem; Integrins in angiogenesis, organism-specific biosystem; Senescence and Autophagy,
Citations
Publication ()
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COA
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