Anti-SAP 2a monoclonal antibody (DMAB7813MH)

Mouse anti-Human SAP 2a monoclonal antibody for ELISA, WB Datasheet

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a synthetic peptide corresponding to amino acids near the N-terminus of human p38/SAPK2α, conjugated to KLH.


Alternative Names
CSAID Binding Protein 1; CSAID binding protein; CSAID-binding protein

Product Background

Antigen Description
p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell differentiation and apoptosis. p38 MAP Kinase (MAPK), also called RK or CSBP, is the mammalian orthologue of the yeast Hog1p MAP kinase, which participates in a signalling cascade controlling cellular responses to cytokines and stress. Four p38 MAP kinases, p38-α (MAPK14), -β (MAPK11), -γ (MAPK12 / ERK6), and -δ (MAPK13 / SAPK4), have been identified. Similar to the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including osmotic shock, inflammatory cyto.


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Stefansson, B; Brautigan, DL; et al. Protein phosphatase 6 subunit with conserved sit4-associated protein domain targets I kappa B epsilon. JOURNAL OF BIOLOGICAL CHEMISTRY 281:22624-22634(2006).
Barancik, M; Htun, P; et al. Okadaic acid and anisomycin are protective and stimulate the SAP/JNK pathway. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 34:182-190(1999).

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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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