Anti-Rheumatoid Factor monoclonal antibody (DMAB6275)

Mouse anti-Human Rheumatoid Factor monoclonal antibody for ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgM
Clone
N310121
Species Reactivity
Human
Immunogen
Purified Human IgMcryoglobulins
Conjugate
Unconjugated

Target


Alternative Names
RF; Rheumatoid Factor;Ig kappa chain V-III region CLL;Ig kappa chain V-III region GOL

Product Background


Antigen Description
Rheumatoid factor (RF) is an autoantibody (antibody directed against an organism"s own tissues) most relevant in rheumatoid arthritis. It is defined as an antibody against the Fc portion of IgG. RF and IgG join to form immune complexes that contribute to the disease process. RF is part of the latest classification criteria of Rheumatoid Arthritis but has got company of the biomarker ACPA (Anti Citrullinated Peptide Antibody). Rheumatoid factor can also be a cryoglobulin (antibody that precipitates on cooling of a blood sample); it can be either type 2 (monoclonal IgM to polyclonal IgG) or type 3 (polyclonal IgM to polyclonal IgG) cryoglobulin.

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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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