P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene. The product of this gene, P2Y2 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene.
Pathway
Class A/1; G alpha (q) signalling events; GPCR downstream signaling; GPCR ligand binding; GPCRs; Neuroactive ligand-receptor interaction; Nucleotide GPCRs; Nucleotide-like (purinergic) receptors; P2Y receptors; Signal Transduction; Signaling by GPCR
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Sukigara, S; Dai, HM; et al. Expression of Astrocyte-Related Receptors in Cortical Dysplasia With Intractable Epilepsy. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 73:798-806(2014).
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