Specifications
Immunogen
Synthetic peptide: QLPPGKPEIFKCRS conjugated to KLH, corresponding to amino acids 1-14 of Human Prolactin Receptor.
Applications
Application Notes
ELISA: 1/250 - 1/1100.
Target
Alternative Names
PRLR; prolactin receptor; AI987712; CLONE SPM213; CPRLP; Delta 4-delta 7/11 truncated prolactin receptor; Delta 4-SF1b truncated prolactin receptor; hPRL receptor; hPRLrI; Lactogen receptor; MGC105486; OPR; OTTHUMP00000115998; Pr-1; Pr-3; PRL R; PRL-R; PR
Product Background
Antigen Description
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
Pathway
Adipogenesis, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; ErbB4 signaling events, organism-specific biosystem; Growth hormone receptor signaling, organism-specific biosystem; Immune System, organism-specific biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosy
Citations
Publication ()
Have you cited CPBT-44281SH in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
