Anti-Human MLH-1 Antibody (DMAB5512MH)

Mouse anti-Human MLH-1 Monoclonal antibody [clone H169-16] for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
H169-16
Immunogen
Full length recombinant MLH.
Conjugate
Unconjugated

Target


Alternative Names
MLH1; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); FCC2; COCA2; HNPCC; hMLH1
Entrez Gene ID
UniProt ID

Product Background


Pathway
BRCA1-associated genome surveillance complex (BASC); Fanconi anemia pathway; Meiosis; Colorectal cancer; Direct p53 effectors; Endometrial cancer; Meiotic Recombination; Mismatch repair; Ovarian Infertility Genes; Pathways in cancer

Citations


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References


Kuan, SF; Navina, S; et al. Immunohistochemical detection of BRAF V600E mutant protein using the VE1 antibody in colorectal carcinoma is highly concordant with molecular testing but requires rigorous antibody optimization. HUMAN PATHOLOGY 45:464-472(2014).
Shia, JR; Tang, LH; et al. Immunohistochemistry as First-line Screening for Detecting Colorectal Cancer Patients at Risk for Hereditary Nonpolyposis Colorectal Cancer Syndrome A 2-antibody Panel May be as Predictive as a 4-antibody Panel. AMERICAN JOURNAL OF SURGICAL PATHOLOGY 33:1639-1645(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Order Info: Anti-Human MLH-1 Antibody

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