Anti-Human MLH-1 Antibody (DMAB5512MH)

Mouse anti-Human MLH-1 Monoclonal antibody [clone H169-16] for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
H169-16
Immunogen
Full length recombinant MLH.
Conjugate
Unconjugated

Target


Alternative Names
MLH1; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); FCC2; COCA2; HNPCC; hMLH1
Entrez Gene ID
UniProt ID

Product Background


Pathway
BRCA1-associated genome surveillance complex (BASC); Fanconi anemia pathway; Meiosis; Colorectal cancer; Direct p53 effectors; Endometrial cancer; Meiotic Recombination; Mismatch repair; Ovarian Infertility Genes; Pathways in cancer

Citations


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References


Barrow, E; Evans, DG; et al. A comparative study of quantitative immunohistochemistry and quantum dot immunohistochemistry for mutation carrier identification in Lynch syndrome. JOURNAL OF CLINICAL PATHOLOGY 64:208-214(2011).
Eccleston, J; Schrader, CE; et al. Class Switch Recombination Efficiency and Junction Microhomology Patterns in Msh2-, Mlh1-, and Exo1-Deficient Mice Depend on the Presence of mu Switch Region Tandem Repeats. JOURNAL OF IMMUNOLOGY 183:1222-1228(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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