Anti-LAG3 monoclonal antibody (CABT-34995MH)

Mouse anti-Human LAG3 monoclonal antibody for ICC/IF, IHC-Fr, IP, Inhib, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
28C5
Species Reactivity
Human, Rhesus monkey
Immunogen
Synthetic peptide: G PPAAAPGHPL APGPHPAAPS SWGPRPRRY, corresponding to amino acids 70-99 of Human Lymphocyte Activation Gene 3
Conjugate
Unconjugated

Applications


Application Notes
IHC-Fr: 1/150; IP: 10 μg/ml; WB: 5 μg/ml; ICC/IF:1/100; Inhibition Assay: 10 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
LAG3; lymphocyte-activation gene 3; lymphocyte activation gene 3 protein; CD223; CD223; FDC protein
Entrez Gene ID
UniProt ID

Citations


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References


Urbanellis, P; Shyu, W; et al. The regulatory T cell effector molecule fibrinogen-like protein 2 is necessary for the development of rapamycin-induced tolerance to fully MHC-mismatched murine cardiac allografts. IMMUNOLOGY 144:91-106(2015).
Balabko, L; Andreev, K; et al. Increased expression of the Th17-IL-6R/pSTAT3/BATF/Ror gamma T-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung. SCIENTIFIC REPORTS 4:-(2014).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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