Anti-Keratan Sulphate monoclonal antibody (DMAB8403)
Mouse anti-Human Keratan Sulphate monoclonal antibody for ELISA, WB, IHC
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Keratan sulphate from skeletal KS type II in human aggrecan.
Carbohydrate chondroitin 6 keratan sulfotransferase 1; Carbohydrate chondroitin 6 keratan sulfotransferase; Carbohydrate keratan sulfate Gal 6 sulfotransferase; Carbohydrate keratan sulfate Gal 6 sulfotransferase 1; Carbohydrate sulfotransferase 1; CHST1
Keratan Sulphate (KS) is sulphated glycosoaminoglycan (GAG) component of proteoglycans found in cornea (KS type I), cartilage, intervertebral disk and other musculoskeletal tissues (KS type II). The KS chains are attached to the core proteins of many matrix proteoglycans eg lumican, keratocan, aggrecan etc. This monoclonal antibody has been raised against skeletal KS type II in human aggrecan. In addition to recognising skeletal KS type II epitopes it recognises corneal KS type I.
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Jander, S; Schroeter, M; et al. Differential regulation of microglial keratan sulfate immunoreactivity by proinflammatory cytokines and colony-stimulating factors. GLIA 30:401-410(2000).
Funderburgh, JL; Corpuz, LM; et al. Mimecan, the 25-kDa corneal keratan sulfate proteoglycan, is a product of the gene producing osteoglycin. JOURNAL OF BIOLOGICAL CHEMISTRY 272:28089-28095(1997).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.