Anti-Keratan Sulphate monoclonal antibody (DMAB8403)
Mouse anti-Human Keratan Sulphate monoclonal antibody for ELISA, WB, IHC
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Keratan sulphate from skeletal KS type II in human aggrecan.
Carbohydrate chondroitin 6 keratan sulfotransferase 1; Carbohydrate chondroitin 6 keratan sulfotransferase; Carbohydrate keratan sulfate Gal 6 sulfotransferase; Carbohydrate keratan sulfate Gal 6 sulfotransferase 1; Carbohydrate sulfotransferase 1; CHST1
Keratan Sulphate (KS) is sulphated glycosoaminoglycan (GAG) component of proteoglycans found in cornea (KS type I), cartilage, intervertebral disk and other musculoskeletal tissues (KS type II). The KS chains are attached to the core proteins of many matrix proteoglycans eg lumican, keratocan, aggrecan etc. This monoclonal antibody has been raised against skeletal KS type II in human aggrecan. In addition to recognising skeletal KS type II epitopes it recognises corneal KS type I.
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Nakayama, F; Umeda, S; et al. Sulfation of keratan sulfate proteoglycan reduces radiation-induced apoptosis in human Burkitt's lymphoma cell lines. FEBS LETTERS 587:231-237(2013).
Stichel, CC; Niermann, H; et al. Basal membrane-depleted scar in lesioned CNS: Characteristics and relationships with regenerating axons. NEUROSCIENCE 93:321-333(1999).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.