Specifications
Species Reactivity
Mouse; Rat; Cow; Dog; Human; Monkey; African green monkey
Immunogen
A synthetic peptide corresponding to residues near the N-term of human GM130.
Applications
Application Notes
ICC/IF: 1/100 - 1/250; IHC-P: 1/250 - 1/500; WB: 1/1000 - 1/10000; IP: 1/50.
Target
Alternative Names
GOLGA2; golgin A2; golgi autoantigen, golgin subfamily a, 2; Golgin subfamily A member 2; GM130; Golgi matrix protein GM130; golgin 95; SY11 protein; 130 kDa cis Golgi matrix protein; 130 kDa cis-Golgi matrix protein; Cis golgi matrix protein GM130; GM130
Product Background
Antigen Description
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined.
Pathway
PLK1 signaling events, organism-specific biosystem.
Citations
Publication ()
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COA
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