Anti-ERCC1 monoclonal antibody (DMAB5461MH)

Mouse anti-Human ERCC1 monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
9G2
Species Reactivity
Human
Immunogen
BALB/C mice were injected with full length recombinant human ERCC1 protein.
Conjugate
Unconjugated

Target


Alternative Names
ERCC1; UV20; COFS4; RAD10; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); DNA excision repair protein ERCC-1
Entrez Gene ID
UniProt ID

Product Background


Pathway
DNA Repair; Dual incision reaction in GG-NER; Dual incision reaction in TC-NER; Fanconi anemia pathway; Formation of incision complex in GG-NER; Formation of transcription-coupled NER (TC-NER) repair complex; Global Genomic NER (GG-NER); Nucleotide Excisi

Citations


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References


Smith, DH; Fiehn, AMK; et al. Measuring ERCC1 protein expression in cancer specimens: Validation of a novel antibody. SCIENTIFIC REPORTS 4:-(2014).
Panov, KI; Panova, TB; et al. RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor. MOLECULAR AND CELLULAR BIOLOGY 26:5436-5448(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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