Anti-EGLN1 monoclonal antibody (CABT-31311RH)

Rabbit anti-Human EGLN1 monoclonal antibody for FC, ICC, IHC-P, IP, WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG1
Clone
FQS4772
Species Reactivity
Mouse, Human
Immunogen
A synthetic peptide corresponding to C terminal residues of Human PHD2 / prolyl hydroxylase.
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 1/200; WB: 1/1000 - 1/10000; IP: 1/10 - 1/100; IHC-P: 1/50 - 1/100; ICC: 1/100 - 1/250; Flow Cyt: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
EGLN1; egl nine homolog 1 (C. elegans); C1orf12,EGL nine (C.elegans) homolog 1; egl nine homolog 1; HIF prolyl hydroxylase 2; HIFPH2
Entrez Gene ID
UniProt ID

Product Background


Pathway
HIF-1-alpha transcription factor network, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; Renal cell carcinoma, organism-specific biosystem; Renal cell carcinoma, conserved biosystem;

Citations


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References


Wolf, G; Schroeder, R; et al. Angiotensin II induces hypoxia-inducible factor-1 alpha in PC 12 cells through a posttranscriptional mechanism: Role of AT(2) receptors. AMERICAN JOURNAL OF NEPHROLOGY 24:415-421(2004).
Shen, C; Shao, ZY; et al. The Caenorhabditis elegans rhy-1 gene inhibits HIF-1 hypoxia-inducible factor activity in a negative feedback loop that does not include vhl-1. GENETICS 174:1205-1214(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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