Anti-Cytokeratin Type II monoclonal antibody (DMABT-52067MH)
Mouse anti-Human Cytokeratin Type II monoclonal antibody for IHC, ELISA, FC, IP, WB
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Human, Bovine, Chicken, Fish, Macaque monkey, Mouse, Rabbit, Rat, Shrew
Human epidermal cells
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
67 kDa cytokeratin; CK1; Cytokeratin 1; Cytokeratin 19; Cytokeratin 8; EHK1
Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The term "cytokeratin" began to be used in the late 1970s (for example, see "Intermediate-sized filaments of human endothelial cells" by Franke, Schmid, Osborn and Weber) when the protein subunits of keratin intermediate filaments inside cells were first being identified and characterized. In 2006 a new systematic nomenclature for keratins was created and now the proteins previously called "cytokeratins" are simply called keratins. Over 25, 000 published articles exist in the biomedical research literature that used the term "cytokeratin".
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Pelletier, MP; Edwardes, MDD; et al. Prognostic markers in resectable non-small cell lung cancer: a multivariate analysis. CANADIAN JOURNAL OF SURGERY 44:180-188(2001).
Lee, MR; Hong, CW; et al. Isolated tumor cells in lymph nodes are not a prognostic marker for patients with stage I and stage II colorectal cancer. JOURNAL OF SURGICAL ONCOLOGY 93:13-18(2006).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.