Anti-Cytokeratin Type II monoclonal antibody (DMABT-52067MH)

Mouse anti-Human Cytokeratin Type II monoclonal antibody for IHC, ELISA, FC, IP, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
BF4
Species Reactivity
Human, Bovine, Chicken, Fish, Macaque monkey, Mouse, Rabbit, Rat, Shrew
Immunogen
Human epidermal cells
Conjugate
Unconjugated

Applications


Application Notes
IHC: Neat
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
67 kDa cytokeratin; CK1; Cytokeratin 1; Cytokeratin 19; Cytokeratin 8; EHK1

Product Background


Antigen Description
Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The term "cytokeratin" began to be used in the late 1970s (for example, see "Intermediate-sized filaments of human endothelial cells" by Franke, Schmid, Osborn and Weber) when the protein subunits of keratin intermediate filaments inside cells were first being identified and characterized. In 2006 a new systematic nomenclature for keratins was created and now the proteins previously called "cytokeratins" are simply called keratins. Over 25, 000 published articles exist in the biomedical research literature that used the term "cytokeratin".

Citations


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References


Pelletier, MP; Edwardes, MDD; et al. Prognostic markers in resectable non-small cell lung cancer: a multivariate analysis. CANADIAN JOURNAL OF SURGERY 44:180-188(2001).
Lee, MR; Hong, CW; et al. Isolated tumor cells in lymph nodes are not a prognostic marker for patients with stage I and stage II colorectal cancer. JOURNAL OF SURGICAL ONCOLOGY 93:13-18(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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