Anti-CFTR monoclonal antibody (CABT-32594MH)

Mouse anti-Human CFTR monoclonal antibody for FC, IHC-Fr, IHC-P Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
N4B8
Species Reactivity
Human
Immunogen
Recombinant protein encoding NBF 2 domain of human CFTR.
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 1/50 - 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CFTR; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); ABCC7, CF,cystic fibrosis transmembrane conductance regulator, ATP binding cassette (sub family C, member 7); cystic fibrosis transmembrane conductanc
Entrez Gene ID
UniProt ID

Product Background


Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem; Pancreatic secretion, organism-specific biosystem; Pancreatic secretion, conserved biosystem; Transmembrane transport of small molecules, organism-specific biosystem

Citations


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References


Krones, E; Graziadei, I; et al. Evolving concepts in primary sclerosing cholangitis. LIVER INTERNATIONAL 32:352-369(2012).
Verhaeghe, C; Remouchamps, C; et al. Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways. BIOCHEMICAL PHARMACOLOGY 73:1982-1994(2007).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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