Anti-CCR4 monoclonal antibody (CABT-32199MH)

Mouse anti-Human CCR4 monoclonal antibody for ELISA, FC, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
LI-5G6
Species Reactivity
Human
Immunogen
Synthetic peptide from human CCR4
Conjugate
Unconjugated

Applications


Application Notes
ELISA: 1/200 - 1/400; Flow Cyt: 1.2μg/106 cells; ICC/IF: 1μg/106 cells.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CCR4; chemokine (C-C motif) receptor 4; C-C chemokine receptor type 4; CC CKR 4; CD194; ChemR13
Entrez Gene ID
UniProt ID

Product Background


Pathway
Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand b

Citations


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References


Agrawal, L; Vanhorn-Ali, Z; et al. Multiple determinants are involved in HIV coreceptor use as demonstrated by CCR4/CCL22 interaction in peripheral blood mononuclear cells (PBMCs). JOURNAL OF LEUKOCYTE BIOLOGY 72:1063-1074(2002).
Nakagami, Y; Kawashima, K; et al. Novel CC chemokine receptor 4 antagonist RS-1154 inhibits ovalbumin-induced ear swelling in mice. EUROPEAN JOURNAL OF PHARMACOLOGY 624:38-44(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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