BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene. The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of alternative translation initiation sites, including a non-AUG site.
Pathway
Androgen Receptor Signaling Pathway; Protein processing in endoplasmic reticulum
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